| Program |
| Day 1: Thursday, November 1 |
|
| 8:00 – 8:30 | Breakfast and Registration |
| 8:30 – 8:50 | Welcome and Introductions |
| 8:50 – 9:20 | Cody Chiuzan Sample Size Formulae and Application for the Two-Stage Continual Reassessment Method (CRM) Columbia University |
| 9:20 – 9:50 | Kristian Brock A Meta-Analysis of Efficacy and Safety Outcomes in Cancer Dose-Finding Trials University of Birmingham |
| 9:50 – 10:20 | Mark Conaway The Role of Early Stage Trial Design in the Drug Development Process University of Virginia Health System |
| 10:20 – 10:50 | Coffee Break |
| 10:50 – 11:20 | Monia Ezzalfani Novel Dose-Finding Design to Jointly Modeling Repeated Continuous Toxicity Score and Efficacy Data Curie Institute |
| 11:20 – 11:50 | Cynthia Basu Bayesian Approach for Single-Arm Trials Incorporating Historical Information Pfizer Inc. |
| 11:50 – 12:20 | Haiyan Zheng A Robust Bayesian Hierarchical Model to Incorporate Preclinical Animal Data into a Phase I Dose Escalation Trial Lancaster University |
| 12:30 – 14:00 | Lunch @ Granville, 8701 Beverly Blvd. |
| 14:10 – 14:40 | Nolan Wages Shift Models for Dose Finding in Partially Ordered Groups University of Virginia |
| 14:40 – 15:10 | Nate O’Connell The Quasi-Partial Order Continual Reassessment Method: Applying Toxicity Scores to Cancer Phase I Drug Combination Trials Wake Forest School of Medicine |
| 15:10 – 15:40 | Maxine Bennett A Dose-Finding Design for Drug Combinations using a Bayesian 4 Parameter Logistic Model with Penalized D-Optimality Cambridge Institute of Public Health |
| 15:40 – 16:10 | Lucie Biard A Simulation Study of Methods for Handling Disease Progression in Dose-Finding Clinical Trials Columbia University |
| 16:15 | Conclusion |
| 18:30 | Social Dinner @ The Farmhouse, 8500 Beverly Blvd., #113 |
Day 2: Friday, November 2 |
|
| 8:00 – 8:30 | Breakfast |
| 8:30 – 9:00 | Pavel Mozgunov A Benchmark for Dose Finding Studies with Continuous Outcomes Lancaster University |
| 9:00 – 9:30 | Thomas Jaki Information Theory in Dose-Finding: Improving Safety of the CRM Lancaster University |
| 9:30 – 10:00 | Yimei Li Continuous Reassessment Method for Pediatric Phase I Trials Incorporating Concurrent Adult Trials Information University of Pennsylvania |
| 10:00 – 10:20 | Coffee Break |
| 10:20 – 10:50 | Christina Yap Dose-Transition Pathways: Integrating Simple Decision-Making in the Design and Implementation of Model-Based Dose Finding Trials University of Birmingham |
| 10:50 – 11:20 | Mourad Tighiouart A Bayesian Adaptive Phase 1/II Design of Cisplatin and Cabazitaxel in Prostate Cancer with Visceral Metastasis Cedars-Sinai |
| 11:20 – 11:50 | Matthew Schipper Individualized and Adaptive Dose Selection via Utilities University of Michigan |
| 12:15 – 14:00 | Lunch @ Locanda Veneta, 8638 W. 3rd Street |
| 14:00 | Conclusion |
