Metastatic
cutaneous squamous cell carcinoma of the parotid gland: prognostic factors
A Coombs*, A Butler** & R Allison**
*Department
of Otolaryngology Head & Neck Surgery, Dunedin Hospital
** Department
of Otolaryngology Head & Neck Surgery, Christchurch Hospital
Introduction:
Metastatic cutaneous squamous cell
carcinoma (cSCC) is the most common parotid malignancy in Australasia.
Prognostic indicators are not clearly defined and the extent of surgical
resection is controversial.
Aims:
To compare our outcomes following surgery for
metastatic cSCC of the parotid gland to those published in the literature and
to identify prognostic factors associated with reduced disease-specific
survival and locoregional control.
Methods:
Retrospective analysis of 63 patients
who had surgery for metastatic cSCC of the parotid gland at a tertiary hospital
over a 10 year period.
Results:
Five year overall survival was 53%, disease-specific
survival 78% and locoregional control 72%. Immunosuppression and no adjuvant
radiotherapy were associated with a significant reduction in disease-specific
survival. None of the factors analysed had a significant effect on locoregional
control rates.
Conclusions:
More extensive surgery, including
lateral temporal bone resection, may improve local control rates in more
advanced disease. The reduced survival of immunocompromised patients must be
considered when planning their management.