Title: New Diagnosis of Crescentic Immunoglublin A Nephropathy in Pregnancy
C Sammartino¹, E Jarvis^1,2, J Burke^1,3, A Morton^1
1Mater Health Service, Brisbane, Queensland
²Logan Hospital, Brisbane, Queensland
³Princess Alexandra Hospital, Brisbane, Queensland

Background: A 27 year-old primigravida presented with haematuria and proteinuria at five weeks of gestation on a background of recurrent urinary tract infections in childhood and a previous episode of pyelonephritis.

Case Report: At 23 weeks of gestation, the serum creatinine level was found to be 450 mmol/L with nephrotic range proteinuria (4 g/day); clinically consistent with a rapidly progressive glomerulonephritis (RPGN). She was referred to our tertiary referral maternity hospital and renal biopsy demonstrated crescentic immunoglobulin A nephropathy. She was commenced on dialysis and administered pulse intravenous methylprednisolone and oral cyclophosphamide. Delivery was advised at 26 weeks due to deterioration in the foetal condition on doppler ultrasound. Post-partum, the patient was no longer dialysis-dependent, however serum creatinine was in the order of 400 and she was discharged with ongoing treatment.